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Paracetamol is a mild analgesic and antipyretic, and is recommended for the treatment of most painful and febrile conditions, for example, headache including migraine, toothache, neuralgia, colds and influenza, sore throat, backache, rheumatic pain and dysmenorrhoea. Two tablets every four hours as required. Not more than eight tablets in 24 hours Do not take for more than 3 days without consulting your doctor. These doses should not be given more frequently than every four hours nor should more than four doses be given in any 24 hour period. One tablet every four to six hours when necessary to a maximum of four doses in 24 hours.


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Acetaminophen is the major metabolite of acetanilid and phenacetinwhich were once commonly used drugs, and is responsible for their analgesic pain-relieving effects. The drug inhibits prostaglandin synthesis in the central nervous systembut it lacks an anti-inflammatory effect in peripheral nerves. Acetaminophen is much less likely to cause gastrointestinal side effects than aspirinbut overdoses of it can cause fatal liver damage.

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For prolonged use, aspirin is considered safer. Acetaminophen has also been implicated as a hormone disruptor, with prenatal exposure to the drug possibly linked to hyperkinetic and behavioral disorders in children. Research has also linked acetaminophen use to alterations in risk perception and decision making and increased risk-taking behaviour.

The drug is marketed under several trade names, including TylenolTempra, and Panadol.

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Alternate titles: N-acetyl-p-aminophenol, N-para-hydroxy-phenylacetamide, N-para-hydroxyphenylacetamide, paracetamol. Print Cite verified Cite.

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Related Topics: analgesic Tylenol Show more. Understand the theories on how Tylenol acetaminophen or paracetamol relieves pain and reduces fever and know the side effects of its overdose.

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Explore theories on how Tylenol acetaminophen or paracetamol relieves pain. Learn More in these related Britannica articles:. Despite this, acetaminophen is a popular mild analgesic and antipyretic and is a suitable alternative to aspirin for patients who develop severe symptoms of stomach irritation, because it is not as harmful to the gastrointestinal tract.

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Marketed under such trade names as Tylenol and Panadol, acetaminophen became one of the most widely used painkillers in the world. In Axelrod left the hospital to the staff of the section on chemical pharmacology….

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Drugany chemical substance that affects the functioning of living things and the organisms such as bacteria, fungi, and viruses that infect them. Pharmacology, the science of drugs, deals with all aspects of drugs in medicine, including their mechanism of action, physical and chemical properties, metabolism, therapeutics, and toxicity.

Effects of paracetamol

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Paracetamol acetaminophen , is a widely used over-the-counter analgesic pain reliever and antipyretic fever reducer.


Some people use paracetamol by intentionally taking more than the recommended dose, or as an act of self-harm.


Taking too much acetaminophen can cause liver damage, sometimes serious enough to require liver transplantation or cause death.